Structure-function Relationships in Biofilms Characterizing the Staphylococcal Autolysin R2 Repeat Domain
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چکیده
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Activity of the major staphylococcal autolysin Atl.
The major autolysin of Staphylococcus aureus (AtlA) and of Staphylococcus epidermidis (AtlE) are well-studied enzymes. Here we created an atlA deletion mutant in S. aureus that formed large cell clusters and was biofilm-negative. In electron micrographs, the mutant cells were distinguished by rough outer cell surface. The mutant could be complemented using the atlE gene from S. epidermidis. To ...
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15 صفحه اولStructure–function relationships in calpains1
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2020
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2019.11.1115